Jump to content


Chair of the Local Organising Committee

Paula’s research has previously been focused on the development and application of statistical methodology in medicine. Major contributions have been made in the fields of clinical trials methodology, meta-analysis, and in the treatment of epilepsy. More recently Paula has undertaken research around the selection of outcomes for clinical research. In 2002, she was appointed Director of a new Centre for Medical Statistics, now the Department of Biostatistics, at the University of Liverpool. She has been an Associate Director of the NIHR Medicines for Children Research Network and is Director of the MC Clinical Trials Unit. In 2007, Paula became Director of the Clinical Trials Research Centre (CTRC) and has been a member of the UK Clinical Research Collaboration Registered CTU Network Steering Group since its inception.

In 2008, Paula led a successful bid to create the MRC North West Hub for Trials Methodology Research (NWHTMR), focusing on four themes (early phase trial design and analysis, later phase trial design and analysis, patients’ perspectives and efficacy and mechanism evaluation), and developing methods for application across key clinical areas including paediatrics, drug safety, cancer and epilepsy. Paula leads the Trials Feasibility Improvement Network theme within the MRC Health e-Research Centre North. Paula is the lead for the European Commission- and MRC-funded COMET (Core Outcome Measures in Effectiveness Trials) Initiative, endorsed by NIHR and now referred to in NIHR HTA Guidance for Applicants. Paula has been appointed as an NIHR Senior Investigator, 2014-2019.